Research Associate/ Scientist , Protein Science

Location:

Boston, MA

Summary:

Our client is looking for an experienced BS- or MS level Research Associate/ Scientist to join their high profile and growing Protein Science team. The group is responsible for construct design, protein production, QC and analytics. You will play a key role in protein/ antibody production and protein characterization to help advance their library-based display and ML platform.

Objectives and Responsibilities:

• Create and carry out protein engineering, production, and molecular testing experiments, including expression and purification.
• Design and optimise biophysical and biochemical investigations of biotherapeutic compounds for candidate optimization and development using high throughput and/or automated methodologies.
• Work on key scientific advances alongside other protein biochemists and biologists by devising experiments and optimising strategies.
• Collaborate closely with data scientists and machine learning developers to advance the ML/AI platform.
• Manage and direct CROs.
• Internally and at scientific meetings/conferences, present/communicate study findings with cross-functional colleagues.
• Stay scientifically current and contribute to the implementation of new technology and instrumentation.

Requirements:

• A BS degree (with 5+ years of experience), or an MS degree (with 3+ years of experience) in structural biology, chemistry, biology, biochemistry, biomedical engineering, molecular biology, or related field.
• 3-5 years of hands-on experience in protein construct design, protein expression in mammalian cells and purification with AKTA, and biochemical biophysical characterizations (SPR, BLI, DSF, CE-SDS, cIEF, DLS, MALS, mass spec, etc).
• Experience with protein QC (aSEC-HPLC) is a plus.
• Automation and/or library-based screening (Yeast or Phage) experience is preferred.
• Proven experience with protein sequence/structure analysis and characterisation of the sequence-structure-function relationship.
• Strong collaborative, organisational, and presentation abilities
• Ability to lead Research Associates, Technicians, and CROs
• Ability to document, maintain, and provide an organised account of lab work and results