Research Associate Sheffield, England
Job description
Applications are invited for the post of Research Associate to join Sheffield’s Translational Neuro-Oncology Research Group led by Dr. Spencer Collis (Science), Mr. Ola Rominiyi (Translational) and Mr. Yahia Al-Tamimi (Clinical) based within the Department of Oncology and Metabolism at the University of Sheffield’s Medical School as part of a collaborative research project with Dr. Katherine Finegan (University of Manchester).
We are seeking a highly motivated individual to work on a LifeArc Pathfinder funded proof-of-concept pilot project in translational brain tumour research. The aim of the study is nbased on some of our recent published data and aims to assess the efficacy of combining novel ERK5-targeting compounds with current standard of care (SoC) Temozolomide chemotherapy for high-grade gliomas which is used to treat these currently incurable tumours. Specifically, this work will utilise our unique 3D patient-derived primary glioma stem cell-like (GSC) culture models that represent inter-patient, intra-tumoral heterogeneity and post-surgical/residual disease.
You will be a practically skilled, well organised, flexible and committed Researcher who will join the laboratory team led by Dr. Spencer Collis and will conduct laboratory research on a semi-independent basis under the direction of Dr. Collis and Mr. Rominiyi. You will be expected to; design, execute and evaluate experiments; keep excellent experimental records; prepare reports regularly and feed back to other members of the research group. You are also expected to contribute to the preparation of scientific manuscripts, attend and deliver seminars/lab meetings, help supervise undergraduate students and advise post-graduate research students as necessary as part of a collaborative research team. The successful candidate should be strongly motivated, self-driven, able to accept direction and be an excellent team player. Excellent communication and interpersonal skills are expected. You should have a PhD (or be close to completion) in molecular or cell biology or have appropriate equivalent experience. You will have experience in human cell culture growth and manipulation (preferrable stem cell culture), western blotting, immunocytochemistry, cell survival assays (preferrable clonogenic assays) and qPCR.
This post is currently fixed term for 1 year.
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