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This is an exciting opportunity for a graduate Research Assistant to contribute to a better understanding of the innate immune response in Parkinson’s. The project will use human induced Pluripotent Stem cell models to examine activation of inflammatory pathways in microglia, astrocytes and neurons following mitochondrial stress.

The successful candidate will be based at the Sir William Dunn School of Pathology, where the post holder will have responsibility for differentiating iPS cells harbouring Parkinson’s disease-associated mutations to iPS-microglia, astrocytes and neurons, and investigating their cellular phenotype, including bioenergetic assays, immunoassays and high content imaging. The role will require close collaboration with other scientists in the project.

The ideal candidate will have a Life Science degree, or equivalent experience / qualification, and experience of working in a neuroscience or immunology research laboratory environment. It will suit someone who is meticulous in practical work and in record keeping, with excellent organizational skills, and able to provide a very high quality of cell culture and assay output.

You will be required to upload a covering letter/supporting statement, including a brief statement of research interests and experience, CV and the details of two referees as part of your online application. The closing date for applications is Monday 4th September 2023 at midday. Interviews will be held shortly thereafter.