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CPI helps make great ideas and inventions a reality. We’re a team of intelligent people using advances in science and technology to solve the biggest global challenges in healthcare and sustainability.

Through our incredible people and innovation infrastructure, we collaborate with our partners in industry, academia, government, and the investment community to accelerate the development and commercialisation of innovative products.

From health technologies and pharmaceuticals to sustainable food and materials innovations, we turn the entrepreneurial spirit and radical thinking of our people and partners into incredible impact that makes our world a better place.

CPI is looking to recruit a Scientist to join our growing team at the state-of-the-art Medicines Manufacturing Innovation Centre (MMIC). Located in Renfrewshire, the MMIC is a collaboration between CPI, the University of Strathclyde, UK Research & Innovation, Scottish Enterprise, and founding industry partners, AstraZeneca and GSK.

Recently, there has been a rapid increase in the number of oligonucleotide therapeutics in development. Understanding these complex molecules and processes is challenging with huge potential to advance understanding in this area. A new collaborative project at CPI will address this challenge by developing a novel digital tool to allow the simple definition of an oligonucleotide, prediction of impurity profile, identification of impurities from mass spectrometry data, and models describing the relationship between the manufacturing process and product quality.

This role is for a Chemist, and we are looking for someone with a background in synthetic chemistry. Ideally, you will have experience in the synthesis and analysis of oligonucleotides or other macromolecules. This role could be suitable for a recent graduate or a scientist looking to develop skills in the emerging area of oligonucleotide process development and manufacture.

You can read more about the exciting work we are doing on oligonucleotides here.

To see where you would be working and learn more about MMIC, please watch this video:

From unused Scottish land to global health impact: our Medicines Manufacturing Innovation Centre

Medicines Manufacturing Innovation Centre set to Transform UK Pharma

Key tasks in the Chemist role will include (but are not limited) to the below:

• To maintain consistent and documented compliance with all relevant Safety, Health, and Environmental (SHE), Data Integrity (DI), quality, and best practice requirements.
• To set up, plan and execute experimental runs and analyse, interpret, and report the results of these within agreed timescales and standards and in accordance with project requirements.
• Use, troubleshooting, and routine maintenance of oligo synthesizers, preparative chromatography, and other similar equipment
• Use of LC-MS including interpretation of spectra, method development, calibration, and some routine maintenance
• Document lab work and analytical characterization in the electronic lab notebook systems to required standard and preparation of data sets for statistical analysis
• Working with the wider project team to develop daily/weekly task plans
• Dissemination of experimental results through presentations, written reports, data analysis, and trending
• Author, review, and approval of SOPs, methods, and specifications
• To stay abreast of the current state of the art in oligonucleotide synthesis and purification
• To be responsible for the maintenance and calibration of equipment to ensure it operates in a safe and efficient manner and is available to meet the requirements of the project(s).

To be successful, you need to:

• Be educated to Degree level (or equivalent) in a Scientific/Engineering or HNC with industrial experience.
• Possess a foundation of technical knowledge and experience in synthetic chemistry including excellent experimental write-up and data presentation skills.
• Possess a foundation of technical knowledge and experience working with and interpreting of analytical techniques.
• Have strong attention to detail with a thorough approach and good organisational skills.
• Have the ability to work in a fast-paced environment, flexibility to adjust with moving priorities, and ensuring attention to detail remains first class.
• Demonstrate evidence of knowledge-sharing and network-building practice across teams or groups.
• Have the ability to apply limited theoretical and practical tools and techniques to contribute to business activities.
• Be learning and willing to apply your own judgment and initiative within standard scientific practices, as well as an understanding of when to seek advice from colleagues.

It would be great if you also had the following:

• Knowledge and experience of Data Integrity principles.
• Experience in COSHH assessment and other risk assessments in a lab environment.
• In-depth knowledge and practical experience in the synthesis and purification of oligonucleotides or other similar complex molecules using automated synthesizers or purification equipment.
• Experience and technical expertise in the interpretation of LC-MS spectra, especially for large or complex molecules.
• Membership with a relevant professional body.

At CPI, we offer a wide range of benefits to our employees, this includes:

• Up to 36 days holiday, including bank holidays – Plus a holiday purchasing scheme
• Generous pension scheme
• Life assurance and accident insurance schemes
• Flexible working
• Learning and Development Opportunities
• Free parking

Find out more about our culture and benefits.

CPI is an organisation based in the UK. Commencement of employment is conditional to demonstrating right to work in the UK, sponsorship may be available.