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Secondment / Fix-term

We would be happy to consider candidates at a grade 8 or 7 level depending on experience

Our Functional Genomics department at GSK comprises of several disciplines that provide the deep scientific knowledge and technical capabilities required to discover and validate potential novel therapeutic targets through the application of extensive genetic analyses, high throughput genome editing and endophenotyping in well-characterised human cellular and in vivo models.

Together with the ability to draw on genotypic and phenotypic databases from our world-leading partnerships with the UK BioBank and 23andMe, and to interrogate the genome through internal and collaborative efforts with the Altius Institute, Open Targets, and the newly-created Laboratory of Genomics Research (LGR) with CRISPR pioneers Jennifer Doudna and Jonathan Weissman at the University of California, we aim to redefine how the industry approaches drug discovery to deliver transformative medicines for our patients.

An exciting Secondment / Fix-term (till the end of the year) opportunity has opened within the Primary Immune Cell group. Working in a multi-faceted, dynamic, and cutting-edge scientific environment, this laboratory-based role will give you the opportunity: a) to apply your molecular and cell biology expertise to build and support functional genomic screens, b) obtain practical experience in target identification and validation, c) work with key partners across the business and interface collaboratively across local and global matrix teams.

In this role you will

• Design and implement large-scale functional genomic and bespoke disease modelling studies, with a particular focus on immunology, employing physiological- and/or disease-relevant cellular models and assays
• Develop and execute phenotypic assays such as FACS and cellular imaging.
• Employ molecular characterization of samples at genomic, RNA, and protein levels.
• Work in a matrix team environment to enable delivery of project and department objectives to the highest possible scientific standard.
• Ensuring compliance with all GSK R&D data integrity practices, ethics codes, standards and training, and safety training and practices.
• Communicate experimental findings effectively, in written and verbal formats to multiple internal and external stakeholders

Closing Date for Applications: 30th March 2023 (COB)

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.

Why you?

Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

• PhD or equivalent experience in genomics, molecular or cellular biology
• Extensive experience of primary cell culture
• Broad experience and in-depth knowledge in phenotypic assays including FACS
• Experience in a broad range of molecular & cellular biology techniques
• Demonstrable experience solving scientific problems

Preferred Qualifications & Skills:

If you have the following characteristics, it would be a plus:

• Broad experience and in-depth knowledge in CRISPR gene editing at single gene or screening level
• Proven experience in immunology research
• Experience in B or T human primary cell culture
• Familiarity with genetic, proteomic, imaging, and/or other ‘omics technologies
• Ability to formulate and communicate a coherent vision/research plan.
• Strong enterprise behaviour working within multidisciplinary teams.

Why GSK?

Uniting science, technology and talent to get ahead of disease together

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

Find out more:

Annual Report 2021

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on [email protected] or 0808 234 4391. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

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