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Job Specification

We offer:

• Vibrant and dynamic employment – we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and exciting
• Opportunities to develop your skills and yourself – our rapid growth brings greater opportunities for you to learn and grow faster!
• A great team where we all support each other – enjoy your work – after all you spend about a third of your time here!

Our Company: “We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world’s leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges”.

We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We take pride in our professionalism and commitment to always deliver our very best work.

We are based in Hertfordshire, in the town of Hoddesdon. The Hoddesdon campus, consisting of several purpose built scientific and administrative buildings together with a purpose built conference area has more than 5,000m2 of premier R&D space and houses an established Process Chemistry, Analytical Chemistry and Drug Discovery team, and a newly formed Formulation Development department. The Hoddesdon site has state-of-the-art Good Manufacturing Practice (GMP) standard facilities for the development of Active Pharmaceutical Ingredients (API), formulation development and process chemistry. We offer our employees a highly supportive team-work environment, enabling them to develop and liberate their true potential.

PHARMARON HODDESDON PROCESS CHEMISTRY

The UK-based Process Chemistry team builds on a legacy of big-pharma experience and capability, significantly enhanced through integration with Pharmaron’s organization and capacity in China. The group provides premium R&D services in small-molecule CMC to leading pharmaceutical and biotech clients from the US, UK, and mainland Europe.

We were established in 2017, following Pharmaron’s acquisition of the Hoddesdon site from MSD. The leadership team and most of the senior chemists are ex-MSD, and bring decades of experience in the field to working with our partners to manufacture API.

With significant expansion of the group underway, we are looking for talented experienced chemists to join our team.

PHARMARON HODDESDON SITE

The Hoddesdon facilities were built and equipped to the highest big-pharma specifications. These include expanded and brand-new chemistry labs, a modern and state-of-the-art pilot plant, and full integration with Analytical, Material Sciences, and Formulation groups located on the same campus.

Since acquiring the site, Pharmaron has made further massive investments in all departments: more than tripling our lab space, adding new capabilities and equipment, and increasing and modernizing our plant capacity. Fuelled by the high demand for our services and excellent reputation, Hoddesdon is poised for sustained expansion over the next decade. This includes headcount growth in Process Chemistry over the last four years and plans to reach more in the next 2 – 3 years.

PROCESS CHEMISTRY –WHAT WE DO

API Route Design

Our group specializes in designing innovative and scalable routes to API, tailored to our clients’ needs and the asset’s phase of development. We pride ourselves on solving problems that are too complex for other CROs to handle and thrive on coming up with bold solutions to challenging transformations.

Process Development

One of our mantras is “Knowledge, not just data”, and we use our in-depth understanding of each reaction to build safe, robust, and sustainable processes. We have all the tools in-house, including DoE, high-throughput experimentation, and PAT, to ensure each step of a route will operate successfully on any scale it’s needed.

GLP and GMP Manufacture

We have a unique, “chemist-led” operating model, with scale-up performed directly by the same person that developed the process. This means the knowledge stays with the batch as it moves from lab to plant, and allows us to move quickly from grams to kilos. It also makes better process chemists, as full immersion in the pilot plant provides hands-on experience that cannot be learned any other way.

JOB SUMMARY

The Process Chemistry team in the UK provides leading R&D, GMP and API services to our international clients. Having recently undergone a period of growth and expansion with the construction of a new laboratory containing 40 fumehoods, we are looking for a number of Scientists and Senior Scientists with a strong background in synthetic organic chemistry to join our expanding team.

Your role will be primarily in designing and developing novel synthetic routes to pharmaceutical APIs in the laboratory and implementing the processes at kilogram-scale in our state-of-the-art pilot plant facility.

• We offer a competitive salary and a progressive and a comprehensive suite of employee benefits
• We offer state of the art working environment in our modern Hoddesdon site
• We offer the opportunity for growth and development and will support funding for relevant training and development programmes

KEY ROLES AND RESPONSIBILITIES

Contributing to the chemistry project by performing experiments and interpreting the results.

Maintaining clear and accurate records of experiments in laboratory notebooks in accordance with company policy.

Working as part of the project team to ensure delivery timelines and API quality.

Learning expertise in core laboratory skills required to support development and scale up of chemical processes.

Complying with all safety and GMP guidelines.

Qualification

• Scientist: A minimum of a MSc in Chemistry with a minimum of 2:1 qualification.
• Senior Scientist: A minimum of a Ph.D or post-doc in Synthetic Organic Chemistry.

Essential Requirements:

• Experience is not a prerequisite, but typically up to 2 years prior academic or industrial laboratory exposure is helpful.
• Ability to effectively contribute to multi-disciplinary scientific teams.
• Excellent communication skills.
• Team player.

SOME OF OUR BENEFITS

• Competitive salary enhanced with Pharmaron discretionary, performance-based bonus

• Company-provided medical insurance, generous flexible benefits scheme, matching pension contribution, and 25-days annual leave (+bank holidays)

• Defined and transparent career progression scheme in an organization with room to advance yourself and continue to grow, alongside a group of talented peers

• A chance to be a part of an expanding company committed to scientific excellence, in a diverse and supportive team where your experience and abilities will stand out and be valued

WHY SHOULD YOU APPLY?

• This is an opportunity for you as a MSc or PhD Graduate, Post-Doc Researcher or Scientist to make a real impact in a highly scientific and regulated environment, demonstrate leadership, ambition, and the desire to grow with the department.
• Build and shape your career in an environment that sets and commits to the highest standards of Chemistry.
• To be part of a team who support each other, embrace, and solve technical challenges and put excellence at the heart of all that we do.

Founded in 2004, Pharmaron is a cutting-edge, fully integrated pharmaceutical R&D service platform supporting the life science industry. The company has invested in its people and facilities and established its comprehensive service offerings throughout the pharmaceutical R&D lifecycle. With operations in China, the US and the UK staffed by more than 19,000 employees, Pharmaron has an excellent track record in delivering end-to-end R&D solutions to its partners globally and enabling them to accelerate their novel drug discovery and development process.