Research Assistant in Cancer Biology

Overview of the Role

Are you a researcher looking for your first challenge? Do you have a background in molecular and cell biology? Do you want to further your career in one of the UK’s leading research intensive Universities?

You will pursue a project aimed at identifying the molecular mechanisms that lead to the pathogenesis of B cell-derived malignancies, including lymphomas and multiple myeloma. This project builds from our previous work that has identified the mechanisms of transcription factors that are often erroneously activated in B-cell tumours due to genetic mutations in the tumour-precursor cells.

The project will aim to understand the oncogenic function of these transcription factors in the pathogenesis of non-Hodgkin lymphoma and multiple myeloma, and to identify new molecular targets for the treatment of these tumours. This is the most critical step towards the realization of precision medicine in the treatment of these currently incurable malignancies. You will make use of a large spectrum of techniques, including in vitro assay systems (cell lines and primary lymphoid/tumour cells), flow cytometry, genomics approaches, and transgenic mouse models.

To explore the post further or for any queries you may have, please contact:

Salvatore Papa, Associate Professor

Email: [email protected]

Additional Information

Find out more about Dr Papa and his research: https://medhealth.leeds.ac.uk/profile/900/1685/dr_salvatore_papa

External lab webpage: https://papa-lab.wixsite.com/papalab

Find out more about the Faculty of Medicine and Health and the School of Medicine.

Find out more about the Leeds Institute of Medical Research at St James’s

The institute and its facilities are predominantly based on the St James’s University Hospitals Campus although some team are also located on the University of Leeds’ main campus.

Find out more about Athena Swan in the Faculty.

Working at Leeds

We are a campus based community and regular interaction with campus is an expectation of all roles in line with academic and service needs and the requirements of the role. We are also open to discussing flexible working arrangements. To find out more about the benefits of working at the University and what it is like to live and work in the Leeds area visit our Working at Leeds information page.

Our University

As an international research-intensive university, we welcome students and staff from all walks of life. We foster an inclusive environment where all can flourish and prosper, and we are proud of our strong commitment to student education. Within the Faculty of Medicine & Health we are dedicated to diversifying our community and we welcome the unique contributions that individuals can bring, and particularly encourage applications from, but not limited to Black, Asian, people who belong to a minority ethnic community; people who identify as LGBT+; and disabled people. Candidates will always be selected based on merit and ability.

Information for disabled candidates

Information for disabled candidates, impairments or health conditions, including requesting alternative formats, can be found on our Accessibility information page or by getting in touch with us at [email protected]

Criminal Records

This post is subject to the Rehabilitation of Offenders Act 1974 and as such, applicants are required to declare criminal records accordingly. Appointees may also be required to complete a criminal record check from the Disclosure and Barring Service (DBS) and where relevant, equivalent overseas authorities.

Further details:

• Candidate Brief