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You will contribute to understanding the biology of leukaemia stem cell (LSC) and defining their drug-able vulnerabilities in chronic myeloid leukaemia (CML). This work is funded through project grants from both Blood Cancer UK and Leukaemia UK project grant and is based in the laboratory of Professor David Vetrie at the Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow.

As a successful candidate you will also be expected to contribute to the formulation and submission of research publications and research proposals as well as assist in managing and directing this work. Outcomes of this work will result in novel drugs being assessed in clinical trials and in the development of novel biomarkers that predict patient response to current therapies.

Perform the following activities in conjunction with and under the guidance of the Principal/Co Investigator:

1. Plan and conduct assigned research individually or jointly in accordance with the projects’ aims and deliverables, thus aligning with the research vision of the Vetrie laboratory and the research strategies of the School of Cancer Sciences and the College of Medical, Veterinary and Life Sciences (MVLS).

2. Document research output including analysis and interpretation of all data, maintaining records and databases, drafting technical/progress reports and papers as appropriate.

3. Develop and enhance your research profile and reputation and that of School of Cancer Sciences, The University of Glasgow and the Vetrie research team, including contributing to publications of international quality in high profile/quality refereed journals, enhancing the research impact in terms of economic/societal benefit, and gathering indicators of esteem.

4. Contribute to the presentation of work at international and national conferences, at internal and external seminars, colloquia and workshops to develop and enhance our research profile.

5. Contribute to the identification of potential funding sources and to assist in the development of proposals to secure funding from internal and external bodies to support future research.

6. Collaborate with colleagues and participate in team/group meetings/seminars/workshops across the School of Cancer Sciences/MVLS/University of Glasgow and the wider research community.

7. Contribute to the organisation, supervision, mentoring and training of undergraduate and/or postgraduate students and less experienced members of the Vetrie research team to ensure their effective development.

8. Perform administrative tasks related to the activities of the research group and School, including Budgets/Expenditure.

9. Carry out modest Teaching activities (e.g demonstrating etc) and associated admin as assigned by the Head of School and in consultation with Professor Vetrie.

10. Keep up to date with current knowledge and recent advances in the field/discipline of Leukaemia.

11. Engage in continuing professional development activities as appropriate.

12. Undertake any other duties of equivalent standing as assigned by the Head of the School of Cancer Sciences.

13. Contribute to the enhancement of the University’s international profile in line with the University’s Strategic Plan, Inspiring People Changing the World.

A1 SCQF Level 10 (Honours degree) in Biological Sciences or other relevant subject or a cognate discipline, or equivalent.

A2 Specialist theoretical and practical knowledge in leukaemia research.

A3 A comprehensive and up-to-date knowledge of cell biology or cell signalling.

B1 An awarded (or recently submitted or near completion) PhD in subject specialism or equivalent

B2 Previous knowledge of leukaemia biology.

C1 Experience of protein and mRNA analysis using western blotting and q-PCR, flow cytometry, culturing of mammalian cells, and knowledge of molecular biology techniques.

C2 Research creativity and cross-discipline collaborative ability as appropriate.

C3 Excellent communication skills (oral and written), including public presentations and ability to communicate complex data/concepts clearly and concisely

C4 Excellent interpersonal skills including team working and a collegiate approach

C5 Appropriate workload/time/project/budget/people management skills

C6 Extensive IT and data analysis/interpretation skills as appropriate.

C7 Self-motivation, initiative and independent thought/working

C8 Problem solving skills including a flexible and pragmatic approach

D1 Holder of a personal licence and previous recent animal handling experience.

D2 Experience of haemopoietic stem cell assays.

D3 Ability and experience using genetically modified and/or xenograft mouse models.

D4 Basic knowledge of R programming language and the use of computational tools to analyse complex datasets.

E1 Sufficient relevant research experience (or equivalent) appropriate to an early career researcher

E2 Project or subject specific experience

E3 Experience of scientific writing

E4 Proven ability to deliver quality outputs in a timely and efficient manner

E5 Evidence of an emerging track record of publications in a relevant field

Salary will be Grade 6, £30,502 - £34,308 per annum.

This post is full time and has funding for up to 3 years.

As part of Team UofG you will be a member of a world changing, inclusive community, which values ambition, excellence, integrity and curiosity.

As a valued member of our team, you can expect:

1 A warm welcoming and engaging organisational culture, where your talents are developed and nurtured, and success is celebrated and shared.

2 An excellent employment package with generous terms and conditions including 41 days of leave for full time staff, pension - pensions handbook https://www.gla.ac.uk/myglasgow/payandpensions/pensions/, benefits and discount packages.

3 A flexible approach to working.

4 A commitment to support your health and wellbeing, including a free 6-month UofG Sport membership for all new staff joining the University https://www.gla.ac.uk/myglasgow/staff/healthwellbeing/.

We believe that we can only reach our full potential through the talents of all. Equality, diversity and inclusion are at the heart of our values. Applications are particularly welcome from across our communities and in particular people from the Black, Asian and Minority Ethnic (BAME) community, and other protected characteristics who are under-represented within the University. Read more on how the University promotes and embeds all aspects of equality and diversity within our community https://www.gla.ac.uk/myglasgow/humanresources/equalitydiversity/.

We endorse the principles of Athena Swan https://www.gla.ac.uk/myglasgow/humanresources/equalitydiversity/athenaswan/ and hold bronze, silver and gold awards across the University.

We are investing in our organisation, and we will invest in you too. Please visit our website https://www.gla.ac.uk/explore/jobs/ for more information.