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The successful candidate will contribute to a research project utilising both lab and multi-omics platforms to determine transcriptomic and proteomic variation in blast phase chronic myeloid leukaemia to enable the development of novel targeted therapeutic approaches in this disease. The successful candidate will work with Dr Gillian Horne, in close collaboration with Professor Mhairi Copland, Professor Helen Wheadon, Dr Kristina Kirschner (University of Glasgow) and Professor Anthony Whetton (University of Manchester). The successful candidate will also be expected to contribute to the formulation and submission of research publications and research proposals, as well as help manage and direct this complex and challenging project as opportunities allow.

Perform the following activities in conjunction with and under the guidance of the Principal/Co Investigator(s):

1. Plan and conduct assigned research individually or jointly in accordance with the project deliverables and project/group/School/College research strategy

2. Document research output including analysis and interpretation of all data, maintaining records and databases, drafting technical/progress reports and papers as appropriate

3. Develop and enhance your research profile and reputation and that of The University of Glasgow/School/Research Group, including contributing to publications of international quality in high profile journals, enhancing the research impact in terms of economic and societal benefit

4. Contribute to the presentation of work at international and national conferences, at internal and external seminars, colloquia, and workshops to develop and enhance our research profile

5. Contribute to the identification of potential funding sources and to assist in the development of proposals to secure funding from internal and external bodies to support future research

6. Collaborate with colleagues and participate in team/ group/ meetings/ seminars/workshops across the research Group/School/College/University and wider community

7. Contribute to the organisation, supervision, mentoring and training of undergraduate and/or postgraduate students and less experienced members of the project team to ensure their effective development

8. Perform administrative tasks related to the activities of the research group and School, including Budgets/Expenditure

9. Carry out modest Teaching activities [e.g. demonstrating etc.] and associated admin as assigned by the Head of School and in consultation with Principal Investigator

10. Keep up to date with current knowledge and recent advances in the field/discipline

11. Engage in continuing professional development activities as appropriate

12. Undertake any other reasonable duties as required by the Head of School/Director of Research Institute

13. Contribute to the enhancement of the University's international profile in line with the University's Strategic Plan, Inspiring People Changing The World

A1 SCQF Level 10 [Honours degree] in Biological Sciences or a cognate discipline, or equivalent

A2 Specialist theoretical and practical knowledge in a research related field

A3 A comprehensive and up-to-date knowledge of the wider subject area or subject specialism

B1 An awarded [or recently submitted or near completion] PhD in subject specialism or equivalent

B2 Scientific experience within haematopoiesis and malignant haematology, particularly with the culture and manipulation of patient samples

C1 Research creativity and cross-discipline collaborative ability as appropriate

C2 Excellent communication skills [oral and written], including public presentations and ability to communicate complex data/concepts clearly and concisely

C3 Excellent interpersonal skills including team working and a collegiate approach

C4 Appropriate workload/time/project/budget/people management skills

C5 Extensive IT and data analysis/interpretation skills as appropriate

C6 Self-motivation, initiative and independent thought/working

C7 Problem solving skills including a flexible and pragmatic approach

D1 Ability to design, conduct and perform complex experiments, including multiparameter flow cytometry, immunofluorescence, RNAseq, and single cell transcriptomic approaches

D2 Ability and experience of tissue culture, in particular mammalian suspension cell lines and human patient samples (bone marrow and peripheral blood)

D3 Ability to perform basic bioinformatic analysis

E1 Sufficient relevant research experience [or equivalent] appropriate to an early career researcher

E2Experience of scientific writing

E4 Proven ability to deliver quality outputs in a timely and efficient manner

E5 Evidence of an emerging track record of publications in a relevant field

Desirable:

F1 Experience of working in leukaemia field

F2 Experience of working with patient-derived tissue samples and biobanking

F3 Experience in the collection and analysis of data in Flow cytometry and qRT-PCR, including single cell qRT-PCR

Salary will be Grade 6, £31,502 - £35,308 per annum.

This post is full time and has funding for 1 year. The start date is negotiable.

As part of Team UofG you will be a member of a world changing, inclusive community, which values ambition, excellence, integrity and curiosity.

As a valued member of our team, you can expect:

1 A warm welcoming and engaging organisational culture, where your talents are developed and nurtured, and success is celebrated and shared.

2 An excellent employment package with generous terms and conditions including 41 days of leave for full time staff, pension - pensions handbook https://www.gla.ac.uk/myglasgow/payandpensions/pensions/, benefits and discount packages.

3 A flexible approach to working.

4 A commitment to support your health and wellbeing, including a free 6-month UofG Sport membership for all new staff joining the University https://www.gla.ac.uk/myglasgow/staff/healthwellbeing/.

We believe that we can only reach our full potential through the talents of all. Equality, diversity and inclusion are at the heart of our values. Applications are particularly welcome from across our communities and in particular people from the Black, Asian and Minority Ethnic (BAME) community, and other protected characteristics who are under-represented within the University. Read more on how the University promotes and embeds all aspects of equality and diversity within our community https://www.gla.ac.uk/myglasgow/humanresources/equalitydiversity/.

We endorse the principles of Athena Swan https://www.gla.ac.uk/myglasgow/humanresources/equalitydiversity/athenaswan/ and hold bronze, silver and gold awards across the University.

We are investing in our organisation, and we will invest in you too. Please visit our website https://www.gla.ac.uk/explore/jobs/ for more information.