Find More Than 10K+
United Kingdom Jobs

About us

This is an exciting opportunity to join the laboratory of Professor Raleigh in the Research Department of Structural and Molecular Biology in the Division of Biosciences at UCL. The Raleigh laboratory studies protein aggregation and amyloid formation with emphasis on amyloid formation by the polypeptide amylin (also known as IAPP).

Biosciences at UCL is one of the world’s foremost centres for research and teaching in the biological sciences and one of the largest Divisions within UCL, undertaking a significant amount of research and teaching. The Division has a diverse portfolio addressing all areas of biology from protein interactions to cell function, organism development, genetics, population studies and the environment. Computational modelling approaches are frequently used alongside experimental research programmes and much of our research crosses traditional boundaries. Activity is underpinned by high calibre science technology platforms and state of the art equipment. Educational activity includes a range of undergraduate programmes, an expanding number of Masters Programmes and a substantial number of postgraduate research students.

About the role

The main purpose of this position is to prepare the polypeptide hormone amylin (also known as IAPP) and variants of amylin by solid phase peptide synthesis and HPLC, and to characterize their biophysical and biochemical properties. You will join an inter disciplinary team that includes cell biologists, peptide chemists, experts in mass spectroscopy and biophysical studies of amyloid formation.

You will contribute to the team’s research efforts and have the opportunity to conduct your own research project under the supervision and with the guidance of senior PhD scientists. The opportunity for training in basic tissue culture techniques is also available in the team.

This role is an open-ended contract with a funding end date of 21/02/2024 in the first instance.

Please note the salary for this role is on UCL Grade 6B (£34,502 - £36,348 per annum).

This appointment is subject to UCL Terms and Conditions of Service for Research and Professional Services Staff. Please visit https://www.ucl.ac.uk/human-resources/conditions-service-research-teaching-and-professional-services-staff for more information.

A job description and person specification can be accessed at the bottom of this page.

If you have any queries about the role, please contact Professor Raleigh at [email protected]. If you need reasonable adjustments or a more accessible format to apply for this job online or have any queries about the application process, please contact Biosciences staffing at [email protected].

About you

You must have a BSci or equivalent degree in Biochemistry, or Chemistry or Chemical Engineering or Biology, or Biophysics or other relevant subject area and proven knowledge of basic chemistry and protein structure. Experience in basic laboratory skills, as evidenced by practical coursers taken as part of a recognized University Degree or by relevant work experience, is also required. You will assist the team in the solid phase peptide synthesis and in the purification of amylin and amylin variants. You will also work with team members to characterize in vitro amyloid formation by amylin and amylin variants. In addition to conducting the research, you will assist in the communication of results in the form of scientific papers and in scientific presentations at local, national, and international conferences. You will also assist in the maintenance of the laboratory by helping to order and stock reagents and by helping to oversee select items of equipment.

What we offer

Our commitment to Equality, Diversity and Inclusion

As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.

We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce.

These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women.

Our department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.

You can read more about our commitment to Equality, Diversity and Inclusion here: https://www.ucl.ac.uk/equality-diversity-inclusion/