research assistant Cambridge, MA
Nvelop Therapeutics
Full Time
Cambridge, MA
10.56 - 12.04 USD Today
Job description
About Us
Our mission is to develop transformational genetic medicines utilizing novel gene editing delivery technologies, with an emphasis on diseases with significant unmet medical need. Our team is advancing multiple innovative approaches to deliver a variety of therapeutic payloads, focusing initially on gene editing in therapeutically relevant cells and tissues. Our world class scientific founders include Professor David Liu (HHMI, Broad and Harvard) and Professor Keith Joung (MGH and Harvard), and we are funded with a significant capital investment by leading life science venture capital firms including Newpath Partners, Atlas Venture, F-Prime Capital, and 5AM Ventures. We believe that our technology has the potential to positively impact patients suffering from severe genetic diseases, and we are committed to building an excellent, science-driven and diverse team that is passionate about making a difference. Nvelop Therapeutics is a stealth-mode biotechnology company based in Cambridge, MA.
Position Overview
We are seeking a motivated and growth-oriented Research Associate/Senior Research Associate to join our Process Development team. This individual will assist in the optimization and scale up of the cell-based manufacturing process to produce non-viral drug delivery vehicles. Working closely with a multidisciplinary team of research and development scientists, the successful candidate will design and execute experiments optimizing media formulation, cell growth, protein expression, bioreactor format, harvesting strategy, and other aspects of the process to advance Nvelop’s product development goals. The individual will communicate experimental findings on a regular basis across a matrixed team of scientists and engineers.
The ideal candidate will have cell culture experience, with both adherent and suspension cell types. Drive to execute, experimental rigor and scientific curiosity are key! We are a small and growing company, so the ability to work in a fast-paced environment and adapt to evolving priorities is a must.
Job Responsibilities
- Contribute to cell-based process development to help advance Nvelop’s milestones
- Identify and optimize process parameters using a DOE approach
- Design experiments, analyze data, and document laboratory work in electronic lab notebooks
- Contribute ideas and present scientific findings at team meetings
- Assist with regular maintenance of critical laboratory reagents and troubleshooting of advanced equipment
Minimum Requirements
- Bachelor’s degree in chemistry, biology, engineering, or a related field with 0-2 years of industry experience
- Experience with mammalian cell culture (adhesion and/or suspension), aseptic technique and transient transfection
- Strong problem-solving, organization, and communication skills and a can-do attitude
- Ability to work independently as well as part of a team and adapt to a fast-paced environment
- Experience with AAV/LVV production processes and DOE approach for process development are a plus
Additional Requirements:
Full time in-person work is necessary for our laboratory-based positions. We work in facilities that require that all individuals working on-site are vaccinated for COVID-19. Position Title and Salary will be commensurate with Experience
We recognize the value of diversity in our workforce and are committed to building a welcoming and supportive working environment. We consider all qualified applicants without regard to race, religion, color, gender, age, national origin, sexual orientation, gender identity, partnership status, protected veteran status, disability, or any other status protected by federal, state, or local law. Individuals who hold legal work authorization applicable to employment in the United States will be considered without regard to citizenship/alienage.
We are not accepting unsolicited resumes from employment agencies for any employment opportunities at this time.
