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Company Description

Bicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines. Our pipeline includes Bicycle Toxin Conjugates® as well as fully synthetic Bicycle® systemic immune cell agonists and Bicycle tumor-targeted immune cell agonists (Bicycle TICAs) focused on oncology indications with high unmet medical need. Bicycle is headquartered in Cambridge, UK, and our US operations run out of Lexington, MA.

Culture is key and all Bicycle employees actively embrace and role model our company values:

• We are Adventurous. We believe it’s the way to deliver extraordinary results for our patients.
• We are Dedicated to our Mission. You can’t change the world if you don’t have determination.
• We are One Team. We only succeed when we work together.

Job Description

The Laboratory Technician plays a key role in the expansion of Bicycle Therapeutics and will enable the laboratories to function effectively. We are looking for a great team player who has excellent organisational skills and someone who can prioritise, communicate, and flex to the task in hand. This role will involve both practical scientific work and administrative work to support the company and the team activities.

• Providing practical lab support for the Biology and Chemistry teams, acting independently to complete essential support function.
  • The use and maintenance of electronic lab management and ticket systems in liaising directly with scientists to discuss their support requirements.
  • Checking and replenishing reagent, consumables and chemical stock levels, and associated paperwork.
  • Compressed gases management including Liquid Nitrogen
  • Preparing basic solutions e.g., buffers, media, and Plates
  • Maintaining Quality Control systems, including Tissue culture rooms (Mycoplasma testing)
    
• Provide Technician support when required for sample preparation, which includes:
  • The use and maintenance of electronic lab management systems in
  • liaising directly with scientists to discuss their support requirements,
  • creating electronic schedules for protein batches using MS Excel and LIMS system
  • accurate preparation of protein batches, both solid and in solution, using automated and non-automated methods,
  • sample inventory management, keeping accurate records using LIMS system and paper-based records.
    
• Liaising with the Logistics Coordinator in preparing samples in/out in accordance with standard operating procedure by
  • preparing samples for delivery to various contract Research organisations
  • maintaining sample inventory for both shipments to and from external resources.
    
• Overseeing the maintenance and upkeep of laboratory equipment
  • Support the Lab Manager to ensure service schedules/records are maintained and adhered to.
  • Ensure that laboratory equipment is well maintained, including maintaining the health of the communal freezer storage systems.
  • Calibrate equipment such as pH meters.
    
• Ensuring that the laboratories meet Health and Safety requirements and compliance.
  • By keeping all workspaces clean and tidy
  • Writing basic Standard Operating Procedures
  • Maintaining lab records to a high standard
  • Ensuring all data is captured and archived according to data integrity requirements.
  • Updating and maintaining Bicycle’s Chemical Inventory with relevant data (MSDS) and storage locations.
  • Flushing eye wash stations, water outlets and emergency showers weekly.
    
• As part of the Green Labs initiative
  • be proactive in developing and championing greener ways of working within the team and the wider business.
    
• Taking a proactive approach to own professional and career development and ensuring compliance with all necessary training, by
  • using Bicycle Tx ‘Training Wheels’
  • attending all compulsory work-related training
    
• When required ensuring the tasks of the wider team are covered, for example during holiday absences. This will be primarily the tasks of the lab assistant, to include use of glass washing machines, autoclaves, and waste management.

Qualifications

Essential:

• A scientific degree or equivalent industry experience.
• Previous laboratory experience; to include pipetting and sterile techniques.
• Strong understanding of chemical awareness and their associated hazards.
• Competence with the MS Office suite of programmes and ideally a lab-based management system.

Desirable:

• Experience of using a LIMS
• Proven experience and knowledge of automated compound management and lab-based systems

Additional Information

• State-of-the-art campus environment
• Competitive reward package
• 28 days annual leave in addition to bank holidays, plus option to buy up to 5 additional days
• Employer contribution to pension
• Life assurance cover 4x basic salary
• Private Medical Insurance, including optical and dental cover
• Health Cash Plan
• Cycle to work scheme

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.