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Job description

Newcells Biotech provides products and services to the pharmaceutical and biotechnology industry. Our vision is to be recognised as transforming drug discovery by developing the best in vitro biology to mimic and predict how new drugs interact with human tissues and organs.

The company has unique capabilities in the development and commercialisation of 2-D and 3-D (organoid) in vitro assays focused on four distinct tissues; kidney, retina, liver and lung. We work with global pharmaceutical companies to provide important data on the safety, pharmacology and efficacy of new therapies.

We are currently looking for a talented and passionate individual to join our lung platform team and contribute to the development of in-vitro models for the study of fibrotic lung diseases. You will work as part of a growing team of scientists and technicians to develop and characterise models and contribute to the execution of commercial projects with our growing customer base.

This position is located at our laboratories, based in a modern campus, close to the centre of the vibrant city of Newcastle upon Tyne, UK.

We are a team and company that values and are excited by:

· Solving challenging problems that make a difference

· Transparency and honest communication

· Valuing and harnessing diversity

· Scientific excellence and rigour

· Well-being and personal growth

We want to attract talented individuals who share our passion and we offer:

· Full time permanent positions

· A competitive salary with participation in a bonus scheme

· Pension

· Flexible working policy and 25 days holiday per annum on top of bank holidays

· Personal development opportunities including training and publication

· Company events

· Free coffee!

Key Activities and Responsibilities

· Production, and further development of cellular based assays for the study of lung fibrosis, with a key focus on high-content imaging and biomarker analysis.

· Planning and execution of client projects, ensuring compliance with company operating procedures and high standards of record keeping.

· Contribution toward the development of in-vitrolung models such as primary cultures and iPSC derived cell types.

· Routine performance of analytical techniques including flow cytometry, qPCR and immunocytochemistry.

· Management of lung group stock supplies and contribution towards day-to-day operations of the laboratory including stock, equipment maintenance and safety documentation.

Person Specification

Essential

· Scientific graduate with a BSc/MSc in Biomedical/Pharmacological Sciences or Equivalent.

· Prior cell culture experience and ability to work independently using aseptic technique.

· Previous experience and knowledge in molecular biology techniques such as; DNA/RNA isolation, PCR/RT-qPCR, Western blotting, flow cytometry, ELISA, immunohistochemistry/immunocytochemistry.

· Motivation and willingness to learn new laboratory techniques and the ability to be agile and prioritise workloads accordingly.

· Dedicated team player with excellent verbal and written communication skills.

· Excellent organisation skills, including maintenance of accurate and traceable records in-line with company procedures.

· Prior experience in COSHH and risk assessment preparation.

Desirable

· Previous experience in lung physiology/disease and/or epithelial cell biology.

· Previous experience in the culture and/or differentiation of fibroblasts.

· Previous experience in co-culture systems.

· Experience of in vitro drug discovery and/or toxicology.

· Prior experience in GLP and following SOPs.

· Prior experience in COSHH and risk assessment preparation.

Application Process

To apply for this position please send an email including current CV and a covering letter summarising your interest and suitability for this position.

Please title your email “Application for post of Associate Scientist – Cell Based Assays for Drug Development - Lung"

Closing date for applications is on 11th October 2023.

Job Type: Full-time, Permanent

Location: Central Newcastle upon Tyne, UK.

Job Types: Full-time, Permanent

Salary: From £27,500.00 per year

Benefits:

• Company events
• Company pension
• Cycle to work scheme
• Health & wellbeing programme

Schedule:

• Monday to Friday
• Weekend availability

Supplemental pay types:

• Performance bonus

Ability to commute/relocate:

• Newcastle upon Tyne: reliably commute or plan to relocate before starting work (required)

Education:

• Bachelor's (preferred)

Experience:

• Molecular Biology: 1 year (preferred)

Work Location: In person

Application deadline: 11/10/2023