Analytical Development Scientist I/II London, England
Job description
ABOUT US
At Quell we seek to deliver truly innovative, life-changing therapies for our patients. Our vision as a company is to build a major global biopharmaceutical company bringing transformational and valued therapies for a range of autoimmune and inflammatory diseases and preventing rejection in organ transplantation, based on modular engineered Tregs.
OUR COMPANY
Quell Therapeutics Ltd ("Quell"), the world leader in the development of engineered T-regulatory (Treg) cell therapies for serious medical conditions driven by the immune system, announced it has raised $156 million in oversubscribed Series B financing. The financing round was co-led by Jeito Capital, Ridgeback Capital Investments, SV Health Investors and Fidelity Management & Research Company LLC with participation from founding investor Syncona. New investors include British Patient Capital through its Future Fund: Breakthrough program, Janus Henderson Investors, Monashee Investment Management, Point72 and funds managed by Tekla Capital Management LLC.
THE ROLE
Analytical Development Scientist I/II
MAIN RESPONSIBILITIES
- Collaborate with other team members and contribute to the development of analytical methods suitable for the analysis of high-quality cell-based therapeutic products.
- Lead assigned objectives with minimal supervision.
- Lead the development of analytical methods suitable for the testing of cell-based products.
- Lead the evaluation of test methods as fit for purpose for transfer to the QC environment.
- Ability to manage multiple projects simultaneously and cross-functionally.
- Plan and coordinates activities of reports to meet departmental requirements.
- Document analytical method development activities in laboratory notebooks and author analytical method development reports to support regulatory documentation.
- Contribute to analytical method transfer activities to the Quality Control group.
- Work with external service providers.
- Maintain a high-level of professional expertise through familiarity with scientific literature and best industry practices.
- Manages activities of technicians, research associates and scientist Level 1 (20% of time).
- Lead in presenting and defending data in working teams and at lab meetings.
- Any other duties as required (following consultation)
- The post-holder will be responsible for adhering to all health and safety guidance, provided by the Company
EXPERIENCE WE ARE LOOKING FOR
- Experience from a directly relevant biotechnology or pharmaceutical industry (E)
- Experience of working in a busy laboratory environment (E)
- D or MD/ Ph.D in relevant scientific discipline with +3 years academic or industry related experience, Masters/Bachelor degree or native equivalent with 10+ years of directly related experience (E)
- Minimum of 3 years' experience in an Assay Development Role (E)
- Experience developing, implementing, and evaluating assays as fit for purpose (ICH) for the analysis and characterisation of cell-based therapies (E).
- Understanding of critical process parameters (CPP), critical quality attributes (CQA), comparability etc. relating to manufacturing process (E).
- Skills/Specialist knowledge and/or experience with a range of biopharmaceutical and cell-based techniques including some or all of: Aseptic technique, Sterility testing, Cell Counting, Flow cytometry, PCR (ddPCR, dPCR, qPCR), Mammalian cell culture, Potency testing (E).
- Good understanding of cell biology and immunology (E)
- Excellent Problem-Solving Skills (E)
- Ability to interpret complex data and implement new work methods (E)
- Strong verbal and written communication skills (E)
- Flexible, self-motivated, and focused on team outcomes (E)
- Understanding of and familiarity with GMP regulations as applied to Assay Development / evaluation (E)
- Excellent organisational skills with the ability to present results clearly and logically, working co-operatively as part of a team, as well as independently (E)
- Excellent attention to detail and ability to accurately follow SOPs (E)
- Commitment to high quality work (E)
BENEFITS
- Holidays: 25 days per year
- Life Assurance: 4 x base salary
- Group Personal Pension: Auto enrolled at 6% employer contribution, 3% employee contribution
- Private Medical Insurance for your whole family
- Annual Bonus
PERKS
- Fantastic collaborative environment at Translation & Innovation Hub
- Click here for Virtual Tour
- $156 Million Investment including brand new lab equipment, innovative methods, and exposure to cutting edge technology
- Flexible working
- Fast paced and progressive company looking for future leaders and innovators
