12 Month University Industrial Placement Student (UIPS): Oncology DMPK Cambridge, East of England, England
Job description
12 Month University Industrial Placement Student (UIPS): Oncology DMPK
Cambridge, UK
£23,000 Base Salary, Bonus & Flexible Benefits
Do you want to be part of a team of supportive, collaborative and likeminded peers to develop your expertise? Then Astra Zeneca might be the one for you!
About AstraZeneca:
AstraZeneca is a global, science-led, patient-centred biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious disease. But we’re more than a global leading pharmaceutical company. At AstraZeneca, we‘re dedicated to being a Great Place to Work where you are empowered to push the boundaries of science and fuel your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society.
About the University Industrial Placement Student (UIPS) Programme:
Join a Truly Inclusive and Supportive International Team.
As an AstraZeneca placement student, there is a huge network of support available to you. You’ll have a dedicated supervisor, a supportive early talent peer network, and a variety of Employee Resource Groups you can join.
We help and empower each other, and our supervisors are committed to providing you with all the guidance and support you need to build your skills, confidence and capabilities.
Whatever your background and experience, you'll be welcomed and encouraged to speak up, ask questions and share knowledge. You will be a valued part of an international team of truly supportive, collaborative and inclusive individuals.
Are you ready to explore this exciting next step in your career? Apply today!
Cambridge
Cambridge is one of the most exciting bioscience hotspots in the world. The Discovery Centre (DISC), located at the heart of the Cambridge Biomedical Campus, is designed to play a central role in our mission to deliver life-changing medicines to patients. As our largest research and development centre in the UK, it will have more than 2,000 people working across therapy areas and drug discovery and development once fully occupied.
About the Opportunity:
The placement will involve undertaking a wide range of in vitro ADME studies (absorption, distribution, metabolism, elimination) to understand the metabolism, pharmacokinetics, tissue distribution and physico-chemical properties of molecules from the early discovery portfolio to clinical candidates and our marketed drugs. It will include training in the use of mass spectrometry for bioanalytical quantification and structural identification. The successful placement student will work in a matrix environment interacting with colleagues from the UK and US from multiple disciplines. There will also be the opportunity to learn about ADME properties of what is called "new modalities" like PROTACs (Proteolysis Targeting Chimeras) or ADCs (Antibody Drug Conjugates). These are exciting areas where we need to develop understanding of how the properties of these molecules impact their ADME behaviour and subsequently their behaviour in the clinic.
Key Objectives of the Placement:
Learn and perform in-vitro experiments to investigate the ADME properties of drug candidates and report results back to the DMPK project lead.
Design and carry out studies to understand the mechanisms of metabolism and disposition of drug candidates.
Conduct a bespoke set of studies relating to a DMPK portfolio issue as a stand-alone piece of research which could potentially lead to a publication.
Qualification, Skills & Experience
Required:
Currently undertaking an undergraduate or integrated master’s degree within a chemical or biological discipline with the opportunity to spend 1 year in industry starting in September 2024
A desire to learn about DMPK science
Desirable:
Some knowledge of DMPK is desirable but not essential. All the training on the different assays and associated analytical technologies such as mass spectrometry will be provided by the oncology DMPK ADME Team
Why AstraZeneca?
At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting-edge methods and bringing unexpected teams together. Interested? Come and join our journey.
Applications Open: 6th September
Applications Close: 9th October 2023
Assessment Day: November 2023
Start Date: 2nd September 2024
This position is a 12 month fixed term contract.
Where can I find out more?
Our Social Media, Follow AstraZeneca on LinkedIn: https://www.linkedin.com/company/1603/
Inclusion & Diversity: https://careers.astrazeneca.com/inclusion-diversity
Career Site: https://careers.astrazeneca.com/
AstraZeneca is proud to be ranked as a Top 100 ‘Best Student Employer’ in the UK by RateMyPlacement. Browse our reviews here (link)
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
