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Available Job Today About Us:

Domainex is a multi-award winning integrated drug discovery CRO that has been setting the highest standards in drug discovery, with a particular emphasis on small molecule research, since 2001. We work in partnership with clients from a variety of sectors including academic, pharmaceutical, biotechnology and patient foundation organisations around the world. Our vision is to be the pre-eminent partner for innovative drug discovery services that improve the quality of life for people living with disease.

We offer our clients tailored services for every step of the drug discovery process, from expression of recombinant proteins and screening against disease targets to identify hit compounds, through the design and medicinal chemistry optimisation of hits and leads, to take these all the way to pre-clinical drug candidates.

Our multidisciplinary team of scientists works closely with our partners to generate innovative ideas, and to deliver high-quality results and outputs (e.g. crystallography-grade proteins and novel compounds that meet the desired target product profile.

We have established a strong reputation with a very high level of repeat business and a proven record of success, some of which we can illustrate through the publications and case studies our clients have allowed us to put in the public domain. We have received several awards recognising our customer focus and innovative approach to drug discovery.

What Is The Role?

Domainex has a 12 month fixed term maternity cover vacancy for a minimum of a BSc Scientist join our Protein Science Team in a lab-based role. Industrial experience (preferably in a CRO, pharma or biotech setting) would be advantageous. The Protein Science Team offers our clients a comprehensive range of services including: molecular biology; protein production for biochemical and biophysical assays, and for structural biology, including structural analysis of protein-ligand structures by X-ray crystallography.

You will have experience in protein expression (E.coli, insect and/or mammalian), expression optimisation, protein purification optimisation and scale up to multi mg scale for structural analysis, protein QC. You will have demonstratable experience using a range of AKTA chromatography equipment and columns. Experience in protein crystallisation or CryoEM would be a plus.

The successful candidate will be enthusiastic, a quick learner, good communicator, equally comfortable to work independently and as part of a team, have good problem-solving skills, and be able to work effectively in an inter-disciplinary team and on multiple projects whilst maintaining high quality throughout.

What Are The Key Responsibilities?

• Plan and implement experimental protein production or structural biology projects, solving any problems that arise
• Undertake protein expression (E.coli, insect and/or mammalian), expression optimisation, protein purification optimisation and scale up to multi mg scale for structural analysis, protein QC, protein-ligand crystallisation
• Prepare and present oral and written reports on research activities to internal and external audiences
• Actively pursue own personal development
• Support routine laboratory operation and maintenance
• Maintain appropriate awareness of safety procedures, attend required safety training and adhere to laboratory safety rules as defined by the host department
• Ensure that all duties are performed in accordance with organisational standards, policies and procedures.

What Can We Offer You?

Your highly competitive salary will be determined by your qualifications and your experience along with our excellent benefits package of a 5% pension contribution from yourself with a 10% contribution by Domainex; four times salary group life cover scheme; a private medical insurance scheme for you with discounted benefits for your family; an excellent Employee Assistance Programme; annual leave of 25 days plus bank holidays and a day off for your birthday; loyal service awards and other great benefits such as discounted gym membership and a lift share scheme.

We welcome all applications into our already diverse and inclusive workplace where we do all we can to assist each and every member of our fantastic team to reach their full potential in their chosen field. Feel free to apply for this role today or drop us a line to have a chat as there may be other options for you to explore within our growing organisation.