Scientist - Drug Discovery Cambridge, East of England, England
Job description
About the Company
T-Therapeutics is a venture-backed company on a mission to unlock the power of T cells to treat chronic and infectious diseases.
Based on technology from Professor Allan Bradleys laboratory in Cambridge Universitys Department of Medicine, T-Therapeutics has secured significant investment from a blue-chip syndicate of investors to support its drug discovery efforts and prepare candidates for clinical development.
T-Therapeutics was founded in 2022, and we are at the very beginning of our journey to develop transformative T cell derived medicines. To realise our ambition, we are currently building facilities, recruiting staff, and establishing our research operations.
Scientist Drug Discovery
About the Opportunity
We are seeking a scientist to join our Drug Discovery team. The team is focused on harnessing the power of T cell biology in developing novel therapeutics for treating cancer. This an excellent opportunity to contribute to the development of advanced medicines that can impact the lives of patients around the world.
In this role you will be responsible for:
- Generation of expression constructs using molecular cloning techniques
- Work with primary immune cell cultures
- In vitro cell based assay development
- Ex vivo cell based assay development
- In vivo mouse model development and characterisation
- Multi-parameter flow cytometry panel set up and analysis
- Use of our state-of-art TCR pipeline technology for novel candidate discovery
- Precise recording of daily laboratory work
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Establishment, review, and updates of SOPs
About You
PhD degree in a relevant area (e.g. Molecular and cellular biology or relevant discipline with experience in experimental research)- Molecular biology expertise in construct designs
- Experience in cell culture and cell line development
- Cell biology experiences in T cell biology, hematologic cells or cancer cells is desirable
- Immuno-assay techniques such as ELISA, ELISpot, flow-based binding assays, are desirable
- Fluorescent activated cell sorting and analysis
- The ability to evaluate and develop methodologies to achieve desired goals
- Proactive attitude and drive
- Strong communication skills and the ability to work effectively as part of a team
- Attention to detail and ability to multi-task
- Capacity to trouble shoot
- Organised and good time management
You will have the opportunity to contribute to innovative drug development, in an open environment, able to learn all aspects of drug development. T-Therapeutics is also committed to enabling staff to grow professionally in a variety of ways as well as providing the chance to develop cutting-edge technologies.
