Research Technician Sheffield, England
Job description
Applications are invited for the post of Research Technician within an internationally recognised research group in a vibrant and stimulating environment at the Sheffield Institute for Translational Neuroscience (SITraN). We are seeking a highly motivated scientist to join an exciting project. This post is at the translational medicine interface in motor neuron disease (MND) research also known as Amyotrophic Lateral Sclerosis (ALS). We are looking for a practically skilled, well-organised and committed Research Technician who will join the team led by Dr Scott Allen. You will be supporting a lab based project to differentiate induced neuronal progenitor cell (INPCs) from ALS patients into iAstrocytes and investigate how the disease affects the methylglyoxal activated NRF2 pathway. You will be working under the direction of Dr Allen. You will be trained in 1. Differentiating iNPCs into astrocytes, 2. Measuring markers of metabolic and oxidative dysfunction by SDS-PAGE, and western blot. 3. MGO detection protocols 4. High content fluorescent imaging analysis. You will also be expected to keep excellent experimental records; prepare reports regularly for Dr Allen. You are also expected to contribute to the preparation of scientific manuscripts and liaise with other project members including collaborators at the University of Sheffield to coordinate experiments as well as help with general lab duties.
You will have a strong background in molecular and cellular (neuro) biology and should be strongly motivated, self-driven, and able to accept direction and be an excellent team player. Excellent communication, written and interpersonal skills are expected.
This post is fixed-term with a start date of 26th June 2023 and an end date of 25th October 2023. Salary will be competitive and will be set at the appropriate point on the research technician scale.
We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.
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