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Applications are invited for the post of Research Assistant in Developmental Neurobiology based in the Department of Life Sciences. You will undertake research in a vibrant, interdisciplinary research environment with an excellent international reputation.

About the job:

This post has risen as a result of an Academy of Medical Sciences Springboard grant awarded to Dr. Nikolas Nikolaou, and is essential to a programme of work that builds on previous investigations (Nikolaou et al., 2022, Current Biology) to understand the extra-nuclear function of SNRNP70, a major spliceosome protein, in modulating the axonal transcriptome and regulating neuronal connectivity,

You will have a central role in completing an exciting programme of research to determine, validate and characterise the protein interactome of cytoplasmic SNRNP70, using both in vivo zebrafish and in vitro approaches. More broadly, you will have a responsibility for enabling and supporting the ultimate research aims of the laboratory: to uncover novel molecular and cellular mechanisms that regulate the assembly and function of neural circuits and how such processes are linked to neurological and neurodegenerative conditions in humans.

About you:

A degree in biological or biomedical science is essential, as is experience and demonstrated competence in bench work and molecular biology techniques (e.g. PCR, RT-qPCR, cloning, DNA/RNA extraction) and biochemical techniques (e.g. western blotting, immunoprecipitation, mass spectrometry). Experience working with zebrafish, and analysis of large datasets (e.g. RNA-seq transcriptomics, proteomics) are highly desirable.

Excellent microscopy and imaging skills (both live and fixed samples), genetic manipulation (e.g. CRISPR gene editing, transgenesis), and immunohistochemistry are desirable. You must also have excellent laboratory organisational and communication skills as the post includes laboratory management duties. Crucially, you must be a problem solver and a self-starter, as abilities to supervise and train colleagues as well as work independently will also be required.

Further information:

The Department of Life Sciences offers a range of Bioscience and Biomedical degrees including an accredited Pharmacy degree. Our research spans a diverse range of areas, from drug discovery science and healthcare, to evolutionary biology and biodiversity and was ranked as world leading or internationally competitive in the REF2021 assessment.

This is a full-time fixed-term contract until April 2025, with potential for further extension.

For an informal discussion about the role please contact Dr Nikolaou ([email protected]), however, please submit your application via the University website.

What we can offer you:

• a very generous employer contributory pension scheme
• generous annual leave allowance with an additional 5 discretionary days so that you can enjoy a positive work life balance
• we are a family-friendly University and with an increasingly agile workforce, are open to flexible working arrangements
• an excellent reward package that recognises the talents of our diverse workforce
• a wide range of personal and professional development opportunities
• a number of support options available for new and existing staff to help with the cost of some immigration expenses which you may be eligible for: Relocation allowance, Visa Reimbursement, Interest-Free Loan.

We aim to be an inclusive university, where difference is celebrated, respected and encouraged. We have an excellent international reputation with staff from over 60 different nations and have made a positive commitment towards gender equality and intersectionality receiving a Silver Athena SWAN award. We truly believe that diversity of experience, perspectives, and backgrounds will lead to a better environment for our employees and students, so we encourage applications from all genders, backgrounds, and communities, particularly from under-represented groups, and value the positive impact that will have on our teams.

We are very proud to be an autism friendly university and are an accredited Disability Confident Leader; committed to building disability confidence and supporting disabled staff.

Find out from our staff what makes the University of Bath a great place to work. Follow us @UniofBath and @UniofBathJobs on Twitter for more information.