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We are seeking a highly motivated Postgraduate Research Assistant to join our a team of researchers developing genetic therapies for inherited cardiomyopathies. We have recently been awarded the BHF Big Beat Challenge award, a £30 million grant aiming to find genetic cures for inherited cardiomyopathies.

You will be under the supervision of Dr. Alexander Sparrow, Assoc. Prof. Chris Toepfer and Prof. Hugh Watkins in the Division of Cardiovascular Medicine. You will be directly involved in the day to day culture and maintenance of induced pluripotent stem cells (iPSC), differentiation of iPSCs into cardiomyocytes in 2D and 3D experimental formats. You will involve genetic editing strategies using CRISPR/Cas9 and a variety of other cellular and molecular experiments aimed at defining novel cures for inherited cardiomyopathies. You will analyse data from experiments and present them internally at group meetings. Training will be provided for specialist techniques, such as cardiac differentiation and editing approaches. You will be required to work flexible hours (including some weekend work) as necessary.

You are required to hold a BSc 2:1 or higher and / or MSc degree in a relevant discipline (i.e. Developmental, Molecular and Cell Biology, Biochemistry, or Natural Sciences) and have experience in anti-biotic free tissue culture. Experience in CRISPR/Cas9-mediated genome-editing or other genetic editing approaches would be desirable.

This is a full time appointment on a fixed term contract for 3 years and you will be based at the West Wing, John Radcliffe Hospital, Oxford, OX3 9DU.

Applications for this vacancy are to be made online; you will be required to upload a CV and supporting statement which explains how you meet the selection criteria for the post.

Only applications received before 12.00 midday on 13 June 2023 can be considered. Interviews are scheduled to place on 27 June 2023.

The University is an Equal Opportunity Employer