Postdoctoral Training Fellow - Structural Biology of DNA Repair Complexes(ID 608) London, England

The Institute of Cancer Research

Full Time London, England 34344 GBP ANNUAL Today

Job description

Key Information

Salary: Dependent on relevant postdoctoral experience. Future progression is based on annual performance review. If the candidate has not yet been awarded their PhD, the starting salary will be at £34,344 until the successful completion of their viva.

This role is eligible for ICR Sponsorship. Support will be provided for costs associated with Visa application. If you are considering relocating to the UK, further information can be found here.

Duration of Contract: Fixed Term for 2 years initially

Hours per week: 35 hours per week (full time)

Closing Date: 11th June 2023

Job Details

Under the leadership of Dr Basil Greber, we are seeking to appoint a Postdoctoral Training Fellow to join the Structural Biology of DNA Repair Complexes team to perform structural and functional studies of nucleotide excision repair (NER), a key DNA repair pathway in eukaryotic cells.

This is an exciting opportunity where you will reconstitute functional DNA repair complexes, determine of their structures by cryo-EM, and collaborate with other groups to test structure-based hypotheses experimentally and obtain new functional insight into the molecular mechanisms of NER.

You will have access to state-of-the-art cryo-EM facilities with an in-house Glacios microscope equipped with a Falcon 4i direct detector and access to Titan Krios microscopes via the LonCEM consortium and the eBIC facility at the Diamond Light Source. The division also hosts facilities for expression of protein complexes in advanced expression systems such as insect cells as well as a range of instruments for their biophysical characterisation.

General information on post-docs at The ICR can be found here.

Key Requirements

The successful candidate must have a PhD in biochemistry, molecular biology, structural biology, or a related discipline with a proven track record in high-quality research. They should have demonstrable ability to drive a research project and incorporate new techniques, as well as in-depth expertise in biochemistry and molecular biology of DNA-/RNA-protein complexes or knowledge of structure determination by cryo-electron microscopy.

The ICR has a workforce agreement stating that Postdoctoral Training Fellows can only be employed for up to 7 years as PDTF at the ICR, providing total postdoctoral experience (including previous employment at this level elsewhere) does not exceed 10 years

We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Dr. Basil Greber via email on [email protected].

About The Institute of Cancer Research

Why work for us?

As a member of staff, you'll have exclusive access to a range of staff benefits.

The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.

We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.

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