Job description
The Clinical Research Unit (CRU) is a Phase 1 accredited unit, the first NHS trust in England and Wales to achieve this standard. The unit undertakes and delivers clinical trials in patients and healthy volunteers with a particular emphasis on early phase research.
The post of CRU Laboratory Technician will involve working in the CRU lab, assisting with the collection, processing and dispatch of clinical trial specimens and clinical data, and the accurate recording of this information onto any study specific documentation in line with Good Clinical Practice (GCP). The post holder will be expected to have excellent communication and team working skills and will work in a dynamic, multi-disciplined team that specialises in delivering early phase research.
The CRU Laboratory collects, processes and stores biological samples from consenting adult patients and volunteers from a variety of clinical trial studies. All work is carried out to ICH GCP standard
The biological samples are collected, processed and stored according to a set of strict standard operating procedures and under the guidance of all current UK legal and ethical regulations including the Human Tissue Act and Data Protection Act.
The biological samples are processed and stored within the CRU laboratory and repository areas and regularly dispatched to sponsors or research partners in a variety of forms including; whole blood, serum, plasma, formalin fixed paraffin embedded material, cerebral spinal fluid, excreta, frozen tissues (such as biopsies) and as fractionated sub-cellular components such as RNA, DNA and protein.
Liverpool University Hospitals NHS Foundation Trust was created on 1 October 2019 following the merger of two adult acute Trusts, Aintree University Hospital NHS Foundation Trust and the Royal Liverpool and Broadgreen University Hospitals NHS Trust.
The merger provides an opportunity to reconfigure services in a way that provides the best healthcare services to the city and improves the quality of care and health outcomes that patients experience.
The Trust runs Aintree University Hospital, Broadgreen Hospital, Liverpool University Dental Hospital and the Royal Liverpool University Hospital.
It serves a core population of around 630,000 people across Merseyside as well as providing a range of highly specialist services to a catchment area of more than two million people in the North West region and beyond.
To hear more about our achievements click herehttps://www.liverpoolft.nhs.uk/media/13089/1606-annual-report-booklet_final.pdf
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The following tasks and responsibilities are performed according to standard operating procedures within the CRU:
- Prepare samples for processing (labelling and racking of collection/transfer tubes) and prepare study specific documentation prior to patient visits
- Processing of biological samples (such as centrifugation, pipetting, biopsy fixation, preparing blood smears), storing and shipping of biological specimens to various analysis labs according to protocol requirements.
- Co-ordinating courier collections for clinical trial samples.
- Accessing data/information from Trust information systems as required.
- Monitoring and maintaining sample laboratory kits and other consumables for use in CRU studies.
- Performing routine laboratory duties such as preparing solutions, cleaning equipment, weekly stock checks and general housekeeping etc.
- Data collection, and accurate completion of research documentation as appropriate, with meticulous attention to detail
- Perform daily temperature monitoring checks using specialised temperature monitoring software (training provided)
- Exercise independent judgement and initiative when problems arise by taking appropriate action to resolve the problem.
- Liaising with visiting research teams for booking use of the laboratory for the processing and storage of trial samples.
- To meet on a regular basis with the CRU Laboratory Manager for professional support and guidance
- To attend training courses, conferences and study days in order to remain up to date with all relevant aspects of clinical research.
- Deliver training in own discipline
- To be aware of hazards within the laboratory and to comply with COSHH guidelines
- To comply with ICH GCP