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Site Name: UK - London - Brentford, UK - Hertfordshire - Stevenage
Posted Date: Aug 21 2023

377401 Associate Director, Clinical Biomarkers - Experimental Medicine Unit

Are you interested in the development of novel, integrated biomarker work to support projects across clinical development for Oncology? Are you searching for a position where you will be working as a key contributor to clinical matrix team (CMT), medicines development team (MDT) and leading development and integration of biomarker strategy into clinical development plans? If so, the Associate Director, Clinical Biomarkers role within our Experimental Medicine Unit (EMU) could be an ideal opportunity to explore.

In this role you will

• Lead and/or contribute to clinical asset biomarker strategy within early and late-stage clinical development programs to generate data that informs on target engagement, pharmacodynamics, mechanism of action and patient selection.
• Represent EMU Biomarker team at Clinical Matrix Teams (CMT) and clinical trial study teams (ST). As part of the CMT and clinical ST, establishing clear decision-making criteria to enable biomarker-informed clinical decisions.
• Develop and implement novel biomarker assays with robust assay validation.
• Provide input to clinical teams on biomarker-related elements of clinical protocols, lab manuals, regulatory documents, and consent forms.
• Provide scientific expertise and technical guidance to enable timely biomarker sample collection and analysis including from high dimensional assays.
• Execute sample testing plan and deliver high quality biomarker data packages to inform clinical development and regulatory strategy.
• Point of contact for resolving study biomarker issues.
• Collaborate with clinical operations and sample management to ensure biomarker testing and data generation
• Align with the companion diagnostics team to deliver novel precision medicine approaches to select patients for treatment.
• Serve as a point of contact for external vendors and collaborators in support of data generation
• Provide frequent project status updates related to biomarker deliverables

Closing Date for Applications: September 10th, 2023 (COB)

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact 0808 234 4391. This will help us to understand any modifications we may need to make to support you throughout our selection process.

#LI-GSK

Why you?

Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

• MA/MSc, Ph.D. or equivalent experience with significant and varied experience working with integrated biomarker within a clinical development setting; or
• Experience working in the pharmaceutical industry
• Experience in the application of biomarkers in clinical trials
• Experience in high-impact contributions to biomarker discovery and/or assay development
• Experience in conducting biomarker analyses on various clinical sample types and working as part of a clinical study team

Preferred Qualifications & Skills:

If you have the following characteristics, it would be a plus:

• Experience in managing research collaborations, contract laboratories and budgets
• Demonstrated scientific capability as evidenced by publications, research reports, and external presentations.
• Therapeutic work experience in Oncology
• Correlative Science Experience
• Effective verbal and written communication skills relating to colleagues and associates both inside and outside the corporation
• Flexibility to work on multiple projects as the portfolio evolves over time.
• Up to date knowledge and deep understanding of major molecular and genomic assay technologies and platforms
• Deep knowledge of immuno-oncology biology, biomarker strategies and application to clinical trials.
• Experience with clinical flow cytometry, immunohistochemistry and/or immunoassay development
• Knowledge and track-record of working to GCP principles
• Having a strong sense of urgency and excellent skills in prioritization, planning as well as timely execution in a very fast-paced environment
• Strong interpersonal and communication skills as well as ability to thrive in a matrix environment

Why GSK?

Uniting science, technology and talent to get ahead of disease together

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

Find out more:

Annual Report 2021

Why Us?

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organization where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on [email protected] or 0808 234 4391. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

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